Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.S274Y

c.821C>A

Surrounding Variants

1 paper

NM_021871.4

p.G273insFs

c.818_819ins5

1 paper

NM_021871.4

p.G273delFs

c.818delC

1 paper

NM_021871.4

p.G273D

c.818G>A

1 paper

NM_021871.4

p.G272E

c.815G>A

1 paper

NM_021871.4

p.G272R

c.814G>C

1 paper

NM_021871.4

p.G272R

c.814G>A

1 paper

NM_021871.4

p.Y277H

c.829T>C

1 paper

NM_021871.4

p.S276delFs

c.826_827delGA

1 paper

NM_021871.4

p.Y277insFs

c.830_831insA

1 paper

NM_021871.4

p.Y277*

c.831T>G

1 paper

NM_021871.4

p.Y277*

c.831T>A

2 papers

NM_021871.4

p.R271*

c.811C>T