Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.P264L

c.791C>T

Surrounding Variants

2 papers

NM_021871.4

p.E262_R263delFs

c.786_789del4

1 paper

NM_021871.4

p.G265S

c.793G>A

1 paper

NM_021871.4

p.G265A

c.794G>C

1 paper

NM_021871.4

p.G266*

c.796G>T

1 paper

NM_021871.4

p.E268G

c.803A>G

1 paper

NM_021871.4

p.E260G

c.779A>G

1 paper

NM_021871.4

p.M259R

c.776T>G

1 paper

NM_021871.4

p.M259K

c.776T>A

1 paper

NM_021871.4

p.T270I

c.809C>T

1 paper

NM_021871.4

p.R258R

c.772A>C

2 papers

NM_021871.4

p.R271*

c.811C>T

1 paper

NM_021871.4

p.M257V

c.769A>G