Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.P228L

c.683C>T

Surrounding Variants

1 paper

NM_021871.4

p.K227N

c.681A>T

1 paper

NM_021871.4

p.K227N

c.681A>C

1 paper

NM_021871.4

p.K227T

c.680A>C

1 paper

NM_021871.4

p.K227E

c.679A>G

1 paper

NM_021871.4

p.M226I

c.678G>T

1 paper

NM_021871.4

p.K225delFs

c.674delT

1 paper

NM_021871.4

p.M226L

c.676A>T

1 paper

NM_021871.4

p.K225_M226Fs

c.675_676delinsGFs

1 paper

NM_021871.4

p.D231Y

c.691G>T

1 paper

NM_021871.4

p.K225*

c.673A>T

1 paper

NM_021871.4

p.K225Q

c.673A>C

1 paper

NM_021871.4

p.L232L

c.694T>C