Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.K195_D196delFs

c.583_586del4

Surrounding Variants

1 paper

NM_021871.4

p.Y197N

c.589T>A

1 paper

NM_021871.4

p.D196G

c.587A>G

3 papers

NM_021871.4

p.D196_Y197insT

c.586_590ins3

1 paper

NM_021871.4

p.D196N

c.586G>A

1 paper

NM_021871.4

p.E198K

c.592G>A

1 paper

NM_021871.4

p.D199V

c.596A>T

1 paper

NM_021871.4

p.D199E

c.597T>G

1 paper

NM_021871.4

p.D199E

c.597T>A

3 papers

NM_021871.4

p.Q200*

c.598C>T

1 paper

NM_021871.4

p.Q200R

c.599A>G

1 paper

NM_021871.4

p.V192E

c.575T>A

1 paper

NM_021871.4

p.V192I

c.574G>A