Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.C184W

c.552C>G

Surrounding Variants

1 paper

NM_021871.4

p.S179_G182delFs

c.536_546del11

1 paper

NM_021871.4

p.S183fs

c.547_548fs

1 paper

NM_021871.4

p.G182Fs

c.546delinsTATTAAGATCCFs

1 paper

NM_021871.4

p.G182A

c.545G>C

1 paper

NM_021871.4

p.A187T

c.559G>A

1 paper

NM_021871.4

p.G182R

c.544G>C

1 paper

NM_021871.4

p.A187D

c.560C>A

1 paper

NM_021871.4

p.A187delFs

c.559delC

1 paper

NM_021871.4

p.L188V

c.562T>G

1 paper

NM_021871.4

p.R181Q

c.542G>A

4 papers

NM_021871.4

p.R181*

c.541C>T

1 paper

NM_021871.4

p.C180W

c.540T>G