Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.D165G

c.494A>G

Surrounding Variants

1 paper

NM_021871.4

p.D165V

c.494A>T

1 paper

NM_021871.4

p.D165E

c.495T>G

1 paper

NM_021871.4

p.D165E

c.495T>A

1 paper

NM_021871.4

p.D165H

c.493G>C

1 paper

NM_021871.4

p.D165N

c.493G>A

1 paper

NM_021871.4

p.V164insFs

c.491_492insC

1 paper

NM_021871.4

p.V164A

c.491T>C

1 paper

NM_021871.4

p.M166K

c.497T>A

1 paper

NM_021871.4

p.V164D

c.491T>A

2 papers

NM_021871.4

p.V164I

c.490G>A

1 paper

NM_021871.4

p.L163*

c.488T>A

1 paper

NM_021871.4

p.Q162H

c.486G>T