Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.V145A

c.434T>C

Surrounding Variants

1 paper

NM_021871.4

p.V145G

c.434T>G

4 papers

NM_021871.4

p.V145D

c.434T>A

1 paper

NM_021871.4

p.V145I

c.433G>A

3 papers

NM_021871.4

p.K144delFs

c.431_432delTT

3 papers

NM_021871.4

p.R143_K144del2

c.427_431del6

1 paper

NM_021871.4

p.I146V

c.436A>G

1 paper

NM_021871.4

p.I146R

c.437T>G

1 paper

NM_021871.4

p.K144E

c.430A>G

1 paper

NM_021871.4

p.E147K

c.439G>A

2 papers

NM_021871.4

p.R143H

c.428G>A

1 paper

NM_021871.4

p.E147V

c.440A>T

1 paper

NM_021871.4

p.R143S

c.427C>A