Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.E132A

c.395A>C

Surrounding Variants

1 paper

NM_021871.4

p.E132D

c.396G>C

1 paper

NM_021871.4

p.D133N

c.397G>A

1 paper

NM_021871.4

p.S131L

c.392C>T

1 paper

NM_021871.4

p.D133G

c.398A>G

1 paper

NM_021871.4

p.D133E

c.399T>G

2 papers

NM_021871.4

p.S131P

c.391T>C

1 paper

NM_021871.4

p.D133E

c.399T>A

2 papers

NM_021871.4

p.L134L

c.400C>T

1 paper

NM_021871.4

p.L134V

c.400C>G

1 paper

NM_021871.4

p.V130A

c.389T>C

1 paper

NM_021871.4

p.L134L

c.402G>A

1 paper

NM_021871.4

p.R135G

c.403A>G