Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.D124G

c.371A>G

Surrounding Variants

1 paper

NM_021871.4

p.D124H

c.370G>C

1 paper

NM_021871.4

p.N125D

c.373A>G

1 paper

NM_021871.4

p.N125H

c.373A>C

1 paper

NM_021871.4

p.R123H

c.368G>A

1 paper

NM_021871.4

p.R123G

c.367C>G

1 paper

NM_021871.4

p.N122K

c.366C>G

1 paper

NM_021871.4

p.T126A

c.376A>G

2 papers

NM_021871.4

p.N122Splc

c.365-1G>T

2 papers

NM_021871.4

p.N122Splc

c.365-1G>A

1 paper

NM_021871.4

p.N122Splc

c.365-2A>C

2 papers

NM_021871.4

p.Y127*

c.381C>G

2 papers

NM_021871.4

p.Y127*

c.381C>A