Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.D59N

c.175G>A

Surrounding Variants

1 paper

NM_021871.4

p.D59A

c.176A>C

1 paper

NM_021871.4

p.S50_E58delFs

c.150_172del23

1 paper

NM_021871.4

p.E58A

c.173A>C

1 paper

NM_021871.4

p.W60G

c.178T>G

3 papers

NM_021871.4

p.E58K

c.172G>A

1 paper

NM_021871.4

p.W60*

c.179G>A

1 paper

NM_021871.4

p.W60*

c.180G>A

1 paper

NM_021871.4

p.D57G

c.170A>G

1 paper

NM_021871.4

p.D57A

c.170A>C

2 papers

NM_021871.4

p.W60_N61Splc

c.180+1G>T

5 papers

NM_021871.4

p.W60_N61Splc

c.180+1G>C

4 papers

NM_021871.4

p.W60_N61Splc

c.180+1G>A