Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.P53L

c.158C>T

Surrounding Variants

1 paper

NM_021871.4

p.P53S

c.157C>T

1 paper

NM_021871.4

p.F54I

c.160T>A

5 papers

NM_021871.4

p.W52*

c.156G>A

1 paper

NM_021871.4

p.F54S

c.161T>C

1 paper

NM_021871.4

p.S50_F54delFs

c.150_160del11

6 papers

NM_021871.4

p.W52*

c.155G>A

1 paper

NM_021871.4

p.W52R

c.154T>C

3 papers

NM_021871.4

p.C55G

c.163T>G

2 papers

NM_021871.4

p.C55R

c.163T>C

1 paper

NM_021871.4

p.C55F

c.164G>T

1 paper

NM_021871.4

p.D51A

c.152A>C

1 paper

NM_021871.4

p.D51_W52ins10

c.151_155ins30