Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_021871.4

p.K48delFs

c.143_144delTT

Surrounding Variants

1 paper

NM_021871.4

p.D49V

c.146A>T

1 paper

NM_021871.4

p.K48*

c.142A>T

1 paper

NM_021871.4

p.S50L

c.149C>T

1 paper

NM_021871.4

p.S50*

c.149C>G

1 paper

NM_021871.4

p.C47Y

c.140G>A

1 paper

NM_021871.4

p.S50S

c.150A>C

1 paper

NM_021871.4

p.D51_W52ins10

c.151_155ins30

1 paper

NM_021871.4

p.D51N

c.151G>A

1 paper

NM_021871.4

p.D51A

c.152A>C

1 paper

NM_021871.4

p.A46D

c.137C>A

1 paper

NM_021871.4

p.W52R

c.154T>C

1 paper

NM_021871.4

p.A46T

c.136G>A