Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.Q44E

c.130C>G

Surrounding Variants

1 paper

NM_021871.4

p.Q44R

c.131A>G

1 paper

NM_021871.4

p.S45F

c.134C>T

1 paper

NM_021871.4

p.S45S

c.135T>G

1 paper

NM_021871.4

p.A46T

c.136G>A

1 paper

NM_021871.4

p.A46D

c.137C>A

1 paper

NM_021871.4

p.E41D

c.123A>C

1 paper

NM_021871.4

p.E41K

c.121G>A

1 paper

NM_021871.4

p.V40V

c.120G>T

1 paper

NM_021871.4

p.V40V

c.120G>C

1 paper

NM_021871.4

p.C47Y

c.140G>A

1 paper

NM_021871.4

p.V40V

c.120G>A

4 papers

NM_021871.4

p.V39delFs

c.117delA