Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_021871.4

p.R38T

c.113G>C

Surrounding Variants

2 papers

NM_021871.4

p.R38K

c.113G>A

12 papers

NM_021871.4

p.R38S

c.114G>T

12 papers

NM_021871.4

p.R38S

c.114G>C

2 papers

NM_021871.4

p.R38W

c.112A>T

13 papers

NM_021871.4

p.R38G

c.112A>G

1 paper

NM_021871.4

p.V39I

c.115G>A

3 papers

NM_021871.4

p.V39D

c.116T>A

2 papers

NM_021871.4

p.P37L

c.110C>T

1 paper

NM_021871.4

p.P37Q

c.110C>A

1 paper

NM_021871.4

p.P37A

c.109C>G

4 papers

NM_021871.4

p.V39delFs

c.117delA

3 papers

NM_021871.4

p.V40fs

c.118_119fs