Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.V34M

c.100G>A

Surrounding Variants

20 papers

NM_021871.4

p.V34L

c.100G>T

20 papers

NM_021871.4

p.V34L

c.100G>C

1 paper

NM_021871.4

p.V34insFs

c.100dupG

1 paper

NM_021871.4

p.V34V

c.102G>C

1 paper

NM_021871.4

p.G33D

c.98G>A

1 paper

NM_021871.4

p.G33_V34insC

c.97_101ins3

1 paper

NM_021871.4

p.G33S

c.97G>A

27 papers

NM_021871.4

p.R35C

c.103C>T

2 papers

NM_021871.4

p.R35G

c.103C>G

7 papers

NM_021871.4

p.R35S

c.103C>A

32 papers

NM_021871.4

p.R35H

c.104G>A

4 papers

NM_021871.4

p.G32E

c.95G>A