Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_021871.4

p.G32E

c.95G>A

Surrounding Variants

5 papers

NM_021871.4

p.G32*

c.94G>T

3 papers

NM_021871.4

p.G32R

c.94G>C

4 papers

NM_021871.4

p.G32R

c.94G>A

1 paper

NM_021871.4

p.G33_V34insC

c.97_101ins3

1 paper

NM_021871.4

p.G33S

c.97G>A

3 papers

NM_021871.4

p.G31V

c.92G>T

5 papers

NM_021871.4

p.G31E

c.92G>A

1 paper

NM_021871.4

p.G33D

c.98G>A

1 paper

NM_021871.4

p.E30del1

c.88_90delTTC

20 papers

NM_021871.4

p.V34L

c.100G>T

20 papers

NM_021871.4

p.V34L

c.100G>C

1 paper

NM_021871.4

p.V34M

c.100G>A