Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.E30G

c.89A>G

Surrounding Variants

1 paper

NM_021871.4

p.A29A

c.87T>G

3 papers

NM_021871.4

p.G31V

c.92G>T

5 papers

NM_021871.4

p.G31E

c.92G>A

1 paper

NM_021871.4

p.E30del1

c.88_90delTTC

1 paper

NM_021871.4

p.A29V

c.86C>T

1 paper

NM_021871.4

p.A29insFs

c.85_86insG

1 paper

NM_021871.4

p.A29T

c.85G>A

5 papers

NM_021871.4

p.G32*

c.94G>T

3 papers

NM_021871.4

p.G32R

c.94G>C

4 papers

NM_021871.4

p.G32R

c.94G>A

2 papers

NM_021871.4

p.L28P

c.83T>C

4 papers

NM_021871.4

p.G32E

c.95G>A