Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_021871.4

p.A20T

c.58G>A

Surrounding Variants

1 paper

NM_021871.4

p.A20G

c.59C>G

1 paper

NM_021871.4

p.A20E

c.59C>A

1 paper

NM_021871.4

p.D21Y

c.61G>T

1 paper

NM_021871.4

p.D21H

c.61G>C

2 papers

NM_021871.4

p.D21N

c.61G>A

2 papers

NM_021871.4

p.W18_T19Splc

c.55-1G>C

1 paper

NM_021871.4

p.D21G

c.62A>G

1 paper

NM_021871.4

p.S22ins1

c.65_66insATT

1 paper

NM_021871.4

p.G23C

c.67G>T

1 paper

NM_021871.4

p.G23R

c.67G>C

1 paper

NM_021871.4

p.G23S

c.67G>A

1 paper

NM_021871.4

p.G23G

c.69T>G