Varaico: Literature-Extracted Genetic Variants

FGB

368 papers

RefSeq Summary

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is c...

Pfam Domains

Fib_alphaaa 91–234UCSCFibrinogen alpha/beta chain family

Fibrinogen_Caa 237–487UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen beta chain

HGNC Previous Name

fibrinogen, B beta polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_005141.5

p.R74L

c.221G>T

Surrounding Variants

1 paper

NM_005141.5

p.R74G

c.220C>G

4 papers

NM_005141.5

p.R74C

c.220C>T

2 papers

NM_005141.5

p.Y71*

c.213T>A

2 papers

NM_005141.5

p.Y71*

c.213T>G

1 paper

NM_005141.5

p.G69G

c.207T>A

1 paper

NM_005141.5

p.G69D

c.206G>A

1 paper

NM_005141.5

p.A80T

c.238G>A

1 paper

NM_005141.5

p.G68R

c.202G>A

1 paper

NM_005141.5

p.G68R

c.202G>C

2 papers

NM_005141.5

p.I66insFs

c.196_197insT

1 paper

NM_005141.5

p.Q82Q

c.246A>G

2 papers

NM_005141.5

p.K83Fs

c.248_249delinsTFs