Varaico: Literature-Extracted Genetic Variants

FGB

368 papers

RefSeq Summary

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is c...

Pfam Domains

Fib_alphaaa 91–234UCSCFibrinogen alpha/beta chain family

Fibrinogen_Caa 237–487UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen beta chain

HGNC Previous Name

fibrinogen, B beta polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005141.5

p.G103R

c.307G>C

Surrounding Variants

1 paper

NM_005141.5

p.G103R

c.307G>A

1 paper

NM_005141.5

p.G103E

c.308G>A

1 paper

NM_005141.5

p.T108insFs

c.323_324ins10

1 paper

NM_005141.5

p.G109G

c.327A>T

1 paper

NM_005141.5

p.L116M

c.346T>A

2 papers

NM_005141.5

p.Q118*

c.352C>T

1 paper

NM_005141.5

p.Q119H

c.357G>C

1 paper

NM_005141.5

p.E120*

c.358G>T

1 paper

NM_005141.5

p.R121W

c.361A>T

1 paper

NM_005141.5

p.I123V

c.367A>G

1 paper

NM_005141.5

p.I123F

c.367A>T

1 paper

NM_005141.5

p.R124*

c.370A>T