Varaico: Literature-Extracted Genetic Variants

FGB

368 papers

RefSeq Summary

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is c...

Pfam Domains

Fib_alphaaa 91–234UCSCFibrinogen alpha/beta chain family

Fibrinogen_Caa 237–487UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen beta chain

HGNC Previous Name

fibrinogen, B beta polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_005141.5

p.Y269Y

c.807C>T

Surrounding Variants

3 papers

NM_005141.5

p.C270R

c.808T>C

3 papers

NM_005141.5

p.Y269H

c.805T>C

1 paper

NM_005141.5

p.V268L

c.802G>T

1 paper

NM_005141.5

p.Y266*

c.798T>A

1 paper

NM_005141.5

p.Y266*

c.798T>G

6 papers

NM_005141.5

p.Y266C

c.797A>G

1 paper

NM_005141.5

p.N273_T274insFs

c.819_820insT

1 paper

NM_005141.5

p.Y266N

c.796T>A

12 papers

NM_005141.5

p.P265L

c.794C>T

1 paper

NM_005141.5

p.P265S

c.793C>T

3 papers

NM_005141.5

p.E275*

c.823G>T

1 paper

NM_005141.5

p.K264E

c.790A>G