Varaico: Literature-Extracted Genetic Variants

FGB

368 papers

RefSeq Summary

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is c...

Pfam Domains

Fib_alphaaa 91–234UCSCFibrinogen alpha/beta chain family

Fibrinogen_Caa 237–487UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen beta chain

HGNC Previous Name

fibrinogen, B beta polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005141.5

p.L324L

c.972T>A

Surrounding Variants

2 papers

NM_005141.5

p.G325A

c.974G>C

4 papers

NM_005141.5

p.W323*

c.969G>A

4 papers

NM_005141.5

p.W323*

c.968G>A

1 paper

NM_005141.5

p.W323_L324ins10

c.967_971ins30

1 paper

NM_005141.5

p.D327H

c.979G>C

1 paper

NM_005141.5

p.K328R

c.983A>G

1 paper

NM_005141.5

p.E321K

c.961G>A

1 paper

NM_005141.5

p.L332P

c.995T>C

1 paper

NM_005141.5

p.T333A

c.997A>G

1 paper

NM_005141.5

p.R334R

c.1002G>A

1 paper

NM_005141.5

p.M335R

c.1004T>G

2 papers

NM_005141.5

p.M335I

c.1005G>A