Varaico: Literature-Extracted Genetic Variants

FGB

368 papers

RefSeq Summary

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is c...

Pfam Domains

Fib_alphaaa 91–234UCSCFibrinogen alpha/beta chain family

Fibrinogen_Caa 237–487UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen beta chain

HGNC Previous Name

fibrinogen, B beta polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_005141.5

p.G444S

c.1330G>A

Surrounding Variants

3 papers

NM_005141.5

p.G444R

c.1330G>C

2 papers

NM_005141.5

p.N443K

c.1329C>A

2 papers

NM_005141.5

p.N443K

c.1329C>G

1 paper

NM_005141.5

p.G444A

c.1331G>C

1 paper

NM_005141.5

p.N443S

c.1328A>G

2 papers

NM_005141.5

p.R445T

c.1334G>C

1 paper

NM_005141.5

p.P442S

c.1324C>T

1 paper

NM_005141.5

p.Y446C

c.1337A>G

1 paper

NM_005141.5

p.Y447C

c.1340A>G

2 papers

NM_005141.5

p.G449delFs

c.1346delG

1 paper

NM_005141.5

p.G449fs

c.1345_1346fs

1 paper

NM_005141.5

p.G450V

c.1349G>T