Varaico: Literature-Extracted Genetic Variants

FGB

368 papers

RefSeq Summary

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is c...

Pfam Domains

Fib_alphaaa 91–234UCSCFibrinogen alpha/beta chain family

Fibrinogen_Caa 237–487UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen beta chain

HGNC Previous Name

fibrinogen, B beta polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005141.5

p.G460R

c.1378G>C

Surrounding Variants

3 papers

NM_005141.5

p.G464D

c.1391G>A

1 paper

NM_005141.5

p.D455Y

c.1363G>T

1 paper

NM_005141.5

p.V465A

c.1394T>C

4 papers

NM_005141.5

p.W467G

c.1399T>G

14 papers

NM_005141.5

p.W467*

c.1400G>A

14 papers

NM_005141.5

p.W467*

c.1401G>A

1 paper

NM_005141.5

p.M468V

c.1402A>G

1 paper

NM_005141.5

p.Y452N

c.1354T>A

1 paper

NM_005141.5

p.G450V

c.1349G>T

8 papers

NM_005141.5

p.W470*

c.1409G>A

8 papers

NM_005141.5

p.W470*

c.1410G>A

1 paper

NM_005141.5

p.W470C

c.1410G>C