Varaico: Literature-Extracted Genetic Variants

FGFR2

2,640 papers

RefSeq Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family member...

Pfam Domains

Ig_3aa 38–110UCSCImmunoglobulin domain

I-setaa 72–159UCSCImmunoglobulin I-set domain

Ig_3aa 167–257UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 392–668UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fibroblast growth factor receptor 2

HGNC Previous Symbols

KGFR; BEK; CFD1; JWS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

43 papers

NM_000141.5

p.K659N

c.1977G>T

NM_022970.4

p.K660N

c.1980G>T

Surrounding Variants

42 papers

NM_000141.5

p.K659N

c.1977G>C

NM_022970.4

p.K660N

c.1980G>C

1 paper

NM_000141.5

p.K659K

c.1977G>A

1 paper

NM_000141.5

p.K659delFs

c.1976delT

31 papers

NM_022970.4

p.K660M

c.1979A>T

NM_000141.5

p.K659M

c.1976A>T

1 paper

NM_000141.5

p.T660S

c.1978A>T

4 papers

NM_000141.5

p.T660A

c.1978A>G

1 paper

NM_000141.5

p.K659R

c.1976A>G

7 papers

NM_000141.5

p.K659T

c.1976A>C

NM_001144913.1

p.K660T

c.1979A>C

1 paper

NM_000141.5

p.N653_K658delFs

c.1957_1973del17

1 paper

NM_000141.5

p.K659fs

c.1975_1976fs

1 paper

NM_000141.5

p.T660S

c.1979C>G

1 paper

NM_000141.5

p.T660N

c.1979C>A