Varaico: Literature-Extracted Genetic Variants

FGFR2

2,640 papers

RefSeq Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family member...

Pfam Domains

Ig_3aa 38–110UCSCImmunoglobulin domain

I-setaa 72–159UCSCImmunoglobulin I-set domain

Ig_3aa 167–257UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 392–668UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fibroblast growth factor receptor 2

HGNC Previous Symbols

KGFR; BEK; CFD1; JWS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000141.5

p.K658R

c.1973A>G

Surrounding Variants

4 papers

NM_022970.4

p.K659N

c.1977A>T

NM_000141.5

p.K658N

c.1974A>T

2 papers

NM_000141.5

p.K658*

c.1972A>T

3 papers

NM_022970.4

p.K659E

c.1975A>G

NM_000141.5

p.K658E

c.1972A>G

1 paper

NM_000141.5

p.K658K

c.1974A>G

4 papers

NM_022970.4

p.K659N

c.1977A>C

NM_000141.5

p.K658N

c.1974A>C

1 paper

NM_000141.5

p.K659fs

c.1975_1976fs

1 paper

NM_000141.5

p.Y657*

c.1971C>G

1 paper

NM_000141.5

p.Y657*

c.1971C>A

1 paper

NM_000141.5

p.K659*

c.1975A>T

56 papers

NM_000141.5

p.K659E

c.1975A>G

NM_022970.4

p.K660E

c.1978A>G

7 papers

NM_000141.5

p.K659Q

c.1975A>C

31 papers

NM_022970.4

p.K660M

c.1979A>T

NM_000141.5

p.K659M

c.1976A>T