Varaico: Literature-Extracted Genetic Variants

FGFR2

2,640 papers

RefSeq Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family member...

Pfam Domains

Ig_3aa 38–110UCSCImmunoglobulin domain

I-setaa 72–159UCSCImmunoglobulin I-set domain

Ig_3aa 167–257UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 392–668UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fibroblast growth factor receptor 2

HGNC Previous Symbols

KGFR; BEK; CFD1; JWS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000141.5

p.Y656*

c.1968T>A

Surrounding Variants

1 paper

NM_000141.5

p.Y656*

c.1968T>G

1 paper

NM_000141.5

p.Y657H

c.1969T>C

1 paper

NM_000141.5

p.D655_Y656del2

c.1963_1967del6

4 papers

NM_000141.5

p.Y656F

c.1967A>T

3 papers

NM_000141.5

p.Y657F

c.1970A>T

1 paper

NM_000141.5

p.Y657S

c.1970A>C

1 paper

NM_000141.5

p.D655D

c.1965C>T

1 paper

NM_000141.5

p.Y657*

c.1971C>G

1 paper

NM_000141.5

p.D655E

c.1965C>G

2 papers

NM_000141.5

p.D655E

c.1965C>A

1 paper

NM_000141.5

p.Y657*

c.1971C>A

2 papers

NM_000141.5

p.K658*

c.1972A>T