Varaico: Literature-Extracted Genetic Variants

FGFR2

2,640 papers

RefSeq Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family member...

Pfam Domains

Ig_3aa 38–110UCSCImmunoglobulin domain

I-setaa 72–159UCSCImmunoglobulin I-set domain

Ig_3aa 167–257UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 392–668UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fibroblast growth factor receptor 2

HGNC Previous Symbols

KGFR; BEK; CFD1; JWS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000141.5

p.R577R

c.1731A>T

Surrounding Variants

1 paper

NM_000141.5

p.R577R

c.1731A>G

1 paper

NM_000141.5

p.R577R

c.1731A>C

1 paper

NM_000141.5

p.R577fs

c.1729_1730fs

3 papers

NM_000141.5

p.A578S

c.1732G>T

1 paper

NM_000141.5

p.R577L

c.1730G>T

1 paper

NM_000141.5

p.A578P

c.1732G>C

1 paper

NM_000141.5

p.R577P

c.1730G>C

1 paper

NM_000141.5

p.A578T

c.1732G>A

1 paper

NM_000141.5

p.R577Q

c.1730G>A

2 papers

NM_000141.5

p.A578V

c.1733C>T

2 papers

NM_000141.5

p.R577*

c.1729C>T

2 papers

NM_000141.5

p.A578G

c.1733C>G