Varaico: Literature-Extracted Genetic Variants

FGFR2

2,640 papers

RefSeq Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family member...

Pfam Domains

Ig_3aa 38–110UCSCImmunoglobulin domain

I-setaa 72–159UCSCImmunoglobulin I-set domain

Ig_3aa 167–257UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 392–668UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fibroblast growth factor receptor 2

HGNC Previous Symbols

KGFR; BEK; CFD1; JWS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000141.5

p.T404T

c.1212C>G

Surrounding Variants

9 papers

NM_000141.5

p.K405E

c.1213A>G

NM_022970.4

p.K406E

c.1216A>G

2 papers

NM_000141.5

p.K405R

c.1214A>G

1 paper

NM_000141.5

p.T403delFs

c.1209delC

2 papers

NM_000141.5

p.K405N

c.1215G>T

2 papers

NM_001144916.2

p.K290N

c.870G>C

NM_000141.5

p.K405N

c.1215G>C

1 paper

NM_000141.5

p.N402_T404del3

c.1204_1211del9

4 papers

NM_000141.5

p.T403M

c.1208C>T

4 papers

NM_000141.5

p.K406E

c.1216A>G

1 paper

NM_000141.5

p.T403A

c.1207A>G

1 paper

NM_000141.5

p.K406N

c.1218G>T

1 paper

NM_000141.5

p.K406insFs

c.1217dupA

1 paper

NM_000141.5

p.K406K

c.1218G>A