Varaico: Literature-Extracted Genetic Variants

FGFR2

2,640 papers

RefSeq Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family member...

Pfam Domains

Ig_3aa 38–110UCSCImmunoglobulin domain

I-setaa 72–159UCSCImmunoglobulin I-set domain

Ig_3aa 167–257UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 392–668UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fibroblast growth factor receptor 2

HGNC Previous Symbols

KGFR; BEK; CFD1; JWS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

49 papers

NM_000141.5

p.W290R

c.868T>A

Surrounding Variants

39 papers

NM_000141.5

p.W290G

c.868T>G

49 papers

NM_000141.5

p.W290R

c.868T>C

5 papers

NM_000141.5

p.W290L

c.869G>T

1 paper

NM_000141.5

p.Q289H

c.867G>T

1 paper

NM_000141.5

p.W290insFs

c.869_870insT

6 papers

NM_000141.5

p.W290S

c.869G>C

1 paper

NM_000141.5

p.Q289H

c.867G>C

1 paper

NM_000141.5

p.W290*

c.869G>A

1 paper

NM_000141.5

p.W290delFs

c.868delA

1 paper

NM_000141.5

p.P286_Q289del0

c.858_866del9

132 papers

NM_000141.5

p.W290C

c.870G>T

1 paper

NM_000141.5

p.W290fs

c.868_869fs