Varaico: Literature-Extracted Genetic Variants

FGFR2

2,640 papers

RefSeq Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family member...

Pfam Domains

Ig_3aa 38–110UCSCImmunoglobulin domain

I-setaa 72–159UCSCImmunoglobulin I-set domain

Ig_3aa 167–257UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 392–668UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fibroblast growth factor receptor 2

HGNC Previous Symbols

KGFR; BEK; CFD1; JWS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000141.5

p.Q259L

c.776A>T

Surrounding Variants

4 papers

NM_000141.5

p.Q259*

c.775C>T

1 paper

NM_000141.5

p.Q259K

c.775C>A

1 paper

NM_000141.5

p.A260S

c.778G>T

1 paper

NM_000141.5

p.A260T

c.778G>A

2 papers

NM_000141.5

p.A260V

c.779C>T

1 paper

NM_000141.5

p.A260fs

c.778_779fs

1 paper

NM_000141.5

p.A260delFs

c.778_779delGC

3 papers

NM_000141.5

p.G261*

c.781G>T

4 papers

NM_000141.5

p.G261R

c.781G>C

4 papers

NM_000141.5

p.G261R

c.781G>A

1 paper

NM_000141.5

p.I257S

c.770T>G

1 paper

NM_000141.5

p.G261V

c.782G>T