Varaico: Literature-Extracted Genetic Variants

FGFR4

981 papers

RefSeq Summary

The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell pro...

Pfam Domains

I-setaa 153–241UCSCImmunoglobulin I-set domain

Ig_3aa 248–337UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 467–743UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fibroblast growth factor receptor 4

HGNC Alias Symbols

JTK2; CD334; TKF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_213647.3

p.F462L

c.1386C>A

Surrounding Variants

1 paper

NM_213647.3

p.P463S

c.1387C>T

2 papers

NM_213647.3

p.R464W

c.1390C>T

1 paper

NM_213647.3

p.R464fs

c.1390_1391fs

1 paper

NM_213647.3

p.E461K

c.1381G>A

1 paper

NM_213647.3

p.D465N

c.1393G>A

1 paper

NM_213647.3

p.D465Y

c.1393G>T

1 paper

NM_213647.3

p.W460fs

c.1378_1379fs

1 paper

NM_213647.3

p.W460_R466delFs

c.1378_1397del20

2 papers

NM_213647.3

p.R466M

c.1397G>T

1 paper

NM_213647.3

p.L456L

c.1368C>T

1 paper

NM_213647.3

p.L456V

c.1366C>G

2 papers

NM_213647.3

p.V450M

c.1348G>A