Varaico: Literature-Extracted Genetic Variants

FGR

55 papers

RefSeq Summary

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains whi...

Pfam Domains

SH3_1aa 83–130UCSCSH3 domain

SH2aa 144–226UCSCSH2 domain

PK_Tyr_Ser-Thraa 263–512UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FGR proto-oncogene, Src family tyrosine kinase

HGNC Previous Symbol

SRC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005248.3

p.D514G

c.1541A>G

Surrounding Variants

1 paper

NM_005248.3

p.Y507C

c.1520A>G

1 paper

NM_005248.3

p.Y523F

c.1568A>T

1 paper

NM_005248.3

p.P525S

c.1573C>T

1 paper

NM_005248.3

p.R496H

c.1487G>A

1 paper

NM_005248.3

p.C483C

c.1449C>T

1 paper

NM_005248.3

p.V471G

c.1412T>G

1 paper

NM_005248.3

p.I452T

c.1355T>C

1 paper

NM_005248.3

p.E450K

c.1348G>A

1 paper

NM_005248.3

p.P421S

c.1261C>T

1 paper

NM_005248.3

p.A399A

c.1197A>T

1 paper

NM_005248.3

p.L389L

c.1167G>C

1 paper

NM_005248.3

p.D353N

c.1057G>A