Varaico: Literature-Extracted Genetic Variants

FGR

55 papers

RefSeq Summary

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains whi...

Pfam Domains

SH3_1aa 83–130UCSCSH3 domain

SH2aa 144–226UCSCSH2 domain

PK_Tyr_Ser-Thraa 263–512UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FGR proto-oncogene, Src family tyrosine kinase

HGNC Previous Symbol

SRC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005248.3

p.E228Splc

c.683-7C>A

Surrounding Variants

1 paper

NM_005248.3

p.A239T

c.715G>A

1 paper

NM_005248.3

p.M244V

c.730A>G

1 paper

NM_005248.3

p.D254D

c.762C>T

1 paper

NM_005248.3

p.S261G

c.781A>G

1 paper

NM_005248.3

p.S261N

c.782G>A

1 paper

NM_005248.3

p.A289A

c.867G>A

1 paper

NM_005248.3

p.P300L

c.899C>T

1 paper

NM_005248.3

p.A307V

c.920C>T

1 paper

NM_005248.3

p.E328K

c.982G>A

1 paper

NM_005248.3

p.G340D

c.1019G>A

1 paper

NM_005248.3

p.E350K

c.1048G>A

1 paper

NM_005248.3

p.D353N

c.1057G>A