Varaico: Literature-Extracted Genetic Variants

FGR

55 papers

RefSeq Summary

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains whi...

Pfam Domains

SH3_1aa 83–130UCSCSH3 domain

SH2aa 144–226UCSCSH2 domain

PK_Tyr_Ser-Thraa 263–512UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FGR proto-oncogene, Src family tyrosine kinase

HGNC Previous Symbol

SRC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005248.3

p.G2insFs

c.4dupG

Surrounding Variants

1 paper

NM_005248.3

p.M1V

c.1A>G

1 paper

NM_005248.3

p.E17G

c.50A>G

1 paper

NM_005248.3

p.A31V

c.92C>T

1 paper

NM_005248.3

p.P51L

c.152C>T

1 paper

NM_005248.3

p.S75L

c.224C>T

1 paper

NM_005248.3

p.T110I

c.329C>T

1 paper

NM_005248.3

p.G112A

c.335G>C

1 paper

NM_005248.3

p.R118W

c.352C>T

1 paper

NM_005248.3

p.S122S

c.366C>T

1 paper

NM_005248.3

p.E143insFs

c.428dupA

1 paper

NM_005248.3

p.Y145H

c.433T>C

1 paper

NM_005248.3

p.W187*

c.560G>A