Varaico: Literature-Extracted Genetic Variants

FIGNL1

52 papers

RefSeq Summary

This gene encodes a member of the AAA ATPase family of proteins. The encoded protein is recruited to sites of DNA damage where it plays a role in DNA double-strand break repair via homologous recombin...

Pfam Domains

AAAaa 437–567UCSCATPase family associated with various cellular activities (AAA)

AAA_lid_3aa 590–633UCSCAAA+ lid domain

Vps4_Caa 626–671UCSCVps4 C terminal oligomerisation domain

Gene Aliases

HGNC Name

fidgetin like 1

HGNC Previous Name

fidgetin-like 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001287492.4

p.K447R

c.1340A>G

Surrounding Variants

1 paper

NM_001287492.4

p.K447T

c.1340A>C

1 paper

NM_001287492.4

p.L449V

c.1345C>G

1 paper

NM_001287492.4

p.C453R

c.1357T>C

1 paper

NM_001287492.4

p.F440C

c.1319T>G

1 paper

NM_001287492.4

p.G459V

c.1376G>T

1 paper

NM_001287492.4

p.P434T

c.1300C>A

1 paper

NM_001287492.4

p.G432E

c.1295G>A

1 paper

NM_001287492.4

p.R431S

c.1293G>T

1 paper

NM_001287492.4

p.R431S

c.1293G>C

1 paper

NM_001287492.4

p.S464T

c.1391G>C

1 paper

NM_001287492.4

p.L430V

c.1288T>G

1 paper

NM_001287492.4

p.S466C

c.1397C>G