Varaico: Literature-Extracted Genetic Variants

FLI1

203 papers

RefSeq Summary

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a f...

Pfam Domains

SAM_PNTaa 114–198UCSCSterile alpha motif (SAM)/Pointed domain

Etsaa 280–361UCSCEts-domain

Gene Aliases

HGNC Name

Fli-1 proto-oncogene, ETS transcription factor

HGNC Alias Symbols

SIC-1; EWSR2; FLI-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002017.5

p.G277Splc

c.830-6G>A

Surrounding Variants

1 paper

NM_002017.5

p.Q280L

c.839A>T

1 paper

NM_002017.5

p.Q282*

c.844C>T

1 paper

NM_002017.5

p.W284*

c.851G>A

1 paper

NM_002017.5

p.W284*

c.852G>A

1 paper

NM_002017.5

p.S294insFs

c.881_882insC

1 paper

NM_002017.5

p.A297T

c.889G>A

1 paper

NM_002017.5

p.S298R

c.892A>C

1 paper

NM_002017.5

p.S298N

c.893G>A

1 paper

NM_002017.5

p.W302*

c.905G>A

2 papers

NM_002017.5

p.E303K

c.907G>A

1 paper

NM_002017.5

p.G307R

c.919G>A

1 paper

NM_002017.5

p.G307R

c.919G>C