Varaico: Literature-Extracted Genetic Variants

FLI1

203 papers

RefSeq Summary

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a f...

Pfam Domains

SAM_PNTaa 114–198UCSCSterile alpha motif (SAM)/Pointed domain

Etsaa 280–361UCSCEts-domain

Gene Aliases

HGNC Name

Fli-1 proto-oncogene, ETS transcription factor

HGNC Alias Symbols

SIC-1; EWSR2; FLI-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002017.5

p.K380N

c.1140G>T

Surrounding Variants

1 paper

NM_002017.5

p.K380N

c.1140G>C

2 papers

NM_002017.5

p.S376L

c.1127C>T

1 paper

NM_002017.5

p.H392del1

c.1174_1176delCAT

1 paper

NM_002017.5

p.Q367*

c.1099C>T

1 paper

NM_002017.5

p.A366V

c.1097C>T

1 paper

NM_002017.5

p.G364D

c.1091G>A

1 paper

NM_002017.5

p.G364A

c.1091G>C

1 paper

NM_002017.5

p.V398delFs

c.1192delG

1 paper

NM_002017.5

p.N399D

c.1195A>G

1 paper

NM_002017.5

p.D361Y

c.1081G>T

1 paper

NM_002017.5

p.P402fs

c.1204_1205fs

1 paper

NM_002017.5

p.P403L

c.1208C>T