Varaico: Literature-Extracted Genetic Variants

FLI1

203 papers

RefSeq Summary

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a f...

Pfam Domains

SAM_PNTaa 114–198UCSCSterile alpha motif (SAM)/Pointed domain

Etsaa 280–361UCSCEts-domain

Gene Aliases

HGNC Name

Fli-1 proto-oncogene, ETS transcription factor

HGNC Alias Symbols

SIC-1; EWSR2; FLI-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002017.5

p.*453W

c.1358A>G

Surrounding Variants

1 paper

NM_002017.5

p.H447D

c.1339C>G

1 paper

NM_002017.5

p.N441D

c.1321A>G

1 paper

NM_002017.5

p.V436I

c.1306G>A

1 paper

NM_002017.5

p.P434L

c.1301C>T

2 papers

NM_002017.5

p.T427M

c.1280C>T

1 paper

NM_002017.5

p.W423*

c.1269G>A

1 paper

NM_002017.5

p.W423*

c.1268G>A

1 paper

NM_002017.5

p.S420P

c.1258T>C

1 paper

NM_002017.5

p.A418T

c.1252G>A

1 paper

NM_002017.5

p.A418P

c.1252G>C

1 paper

NM_002017.5

p.P409P

c.1227T>A

1 paper

NM_002017.5

p.P403L

c.1208C>T