Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 870 variants

13 papers

NM_002019.4

p.P237L

c.710C>T

11 papers

NM_002019.4

p.E144K

c.430G>A

11 papers

NM_002019.4

p.R781Q

c.2342G>A

9 papers

NM_002019.4

p.P1201L

c.3602C>T

8 papers

NM_002019.4

p.R54S

c.162G>C

8 papers

NM_002019.4

p.L154F

c.460C>T

7 papers

NM_002019.4

p.R54S

c.162G>T

6 papers

NM_002019.4

p.R281Q

c.842G>A

6 papers

NM_002019.4

p.M600I

c.1800G>T

6 papers

NM_002019.4

p.M600I

c.1800G>C

6 papers

NM_002019.4

p.M600I

c.1800G>A

6 papers

NM_002019.4

p.A769V

c.2306C>T