Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002019.4

p.E1196G

c.3587A>G

Surrounding Variants

1 paper

NM_002019.4

p.S1199L

c.3596C>T

1 paper

NM_002019.4

p.D1192Y

c.3574G>T

9 papers

NM_002019.4

p.P1201L

c.3602C>T

1 paper

NM_002019.4

p.N1204N

c.3612T>C

2 papers

NM_002019.4

p.S1185*

c.3554C>G

2 papers

NM_002019.4

p.S1185*

c.3554C>A

1 paper

NM_002019.4

p.D1210Y

c.3628G>T

1 paper

NM_002019.4

p.V1211D

c.3632T>A

1 paper

NM_002019.4

p.R1212Splc

c.3635+1G>A

1 paper

NM_002019.4

p.G1178E

c.3533G>A

1 paper

NM_002019.4

p.I1175T

c.3524T>C

1 paper

NM_002019.4

p.Y1169F

c.3506A>T