Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002019.4

p.T770S

c.2308A>T

Surrounding Variants

1 paper

NM_002019.4

p.T770A

c.2308A>G

1 paper

NM_002019.4

p.T770S

c.2309C>G

6 papers

NM_002019.4

p.A769V

c.2306C>T

1 paper

NM_002019.4

p.L771P

c.2312T>C

1 paper

NM_002019.4

p.V767A

c.2300T>C

1 paper

NM_002019.4

p.W773*

c.2318G>A

1 paper

NM_002019.4

p.W773*

c.2319G>A

1 paper

NM_002019.4

p.L762L

c.2286A>G

1 paper

NM_002019.4

p.L778I

c.2332C>A

1 paper

NM_002019.4

p.L759P

c.2276T>C

2 papers

NM_002019.4

p.R781*

c.2341C>T

11 papers

NM_002019.4

p.R781Q

c.2342G>A