Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002019.4

p.L757M

c.2269C>A

Surrounding Variants

1 paper

NM_002019.4

p.L757R

c.2270T>G

1 paper

NM_002019.4

p.N756I

c.2267A>T

1 paper

NM_002019.4

p.E758K

c.2272G>A

1 paper

NM_002019.4

p.S755P

c.2263T>C

1 paper

NM_002019.4

p.L759P

c.2276T>C

1 paper

NM_002019.4

p.S752L

c.2255C>T

1 paper

NM_002019.4

p.T751N

c.2252C>A

1 paper

NM_002019.4

p.L762L

c.2286A>G

1 paper

NM_002019.4

p.G750V

c.2249G>T

1 paper

NM_002019.4

p.V767A

c.2300T>C

6 papers

NM_002019.4

p.A769V

c.2306C>T

1 paper

NM_002019.4

p.T770S

c.2308A>T