Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002019.4

p.R656K

c.1967G>A

Surrounding Variants

1 paper

NM_002019.4

p.E652*

c.1954G>T

1 paper

NM_002019.4

p.K650N

c.1950G>T

1 paper

NM_002019.4

p.K650N

c.1950G>C

2 papers

NM_002019.4

p.K650E

c.1948A>G

1 paper

NM_002019.4

p.G644W

c.1930G>T

1 paper

NM_002019.4

p.A638T

c.1912G>A

1 paper

NM_002019.4

p.Y634F

c.1901A>T

1 paper

NM_002019.4

p.S631A

c.1891T>G

1 paper

NM_002019.4

p.S631T

c.1891T>A

1 paper

NM_002019.4

p.S627C

c.1880C>G

1 paper

NM_002019.4

p.N625insFs

c.1875dupT

1 paper

NM_002019.4

p.N625insFs

c.1874dupA