Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002019.4

p.T599R

c.1796C>G

Surrounding Variants

6 papers

NM_002019.4

p.M600I

c.1800G>T

6 papers

NM_002019.4

p.M600I

c.1800G>C

6 papers

NM_002019.4

p.M600I

c.1800G>A

1 paper

NM_002019.4

p.I604I

c.1812T>C

2 papers

NM_002019.4

p.R593Q

c.1778G>A

3 papers

NM_002019.4

p.R593W

c.1777C>T

1 paper

NM_002019.4

p.K606T

c.1817A>C

1 paper

NM_002019.4

p.Q607K

c.1819C>A

1 paper

NM_002019.4

p.I590F

c.1768A>T

1 paper

NM_002019.4

p.V587D

c.1760T>A

1 paper

NM_002019.4

p.V587F

c.1759G>T

3 papers

NM_002019.4

p.V587I

c.1759G>A