Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002019.4

p.S576Y

c.1727C>A

Surrounding Variants

1 paper

NM_002019.4

p.V579G

c.1736T>G

1 paper

NM_002019.4

p.N580Y

c.1738A>T

1 paper

NM_002019.4

p.L583fs

c.1747_1748fs

1 paper

NM_002019.4

p.T568T

c.1704G>A

3 papers

NM_002019.4

p.T568M

c.1703C>T

1 paper

NM_002019.4

p.D586Y

c.1756G>T

1 paper

NM_002019.4

p.M566fs

c.1696_1697fs

1 paper

NM_002019.4

p.M566delFs

c.1696delT

1 paper

NM_002019.4

p.M566fs

c.1696_1697fs

1 paper

NM_002019.4

p.D586E

c.1758C>G

1 paper

NM_002019.4

p.D586E

c.1758C>A

1 paper

NM_002019.4

p.V587F

c.1759G>T