Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002019.4

p.S318L

c.953C>T

Surrounding Variants

1 paper

NM_002019.4

p.S318A

c.952T>G

1 paper

NM_002019.4

p.V313_P317del5

c.937_950del15

1 paper

NM_002019.4

p.F319L

c.955T>C

1 paper

NM_002019.4

p.F319L

c.957C>G

1 paper

NM_002019.4

p.F319L

c.957C>A

2 papers

NM_002019.4

p.S321F

c.962C>T

1 paper

NM_002019.4

p.R314K

c.941G>A

1 paper

NM_002019.4

p.R312R

c.936T>C

1 paper

NM_002019.4

p.T324A

c.970A>G

1 paper

NM_002019.4

p.R312H

c.935G>A

1 paper

NM_002019.4

p.V326L

c.976G>T

1 paper

NM_002019.4

p.V326L

c.976G>C