Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002019.4

p.R281Q

c.842G>A

Surrounding Variants

1 paper

NM_002019.4

p.R281*

c.841C>T

1 paper

NM_002019.4

p.I282F

c.844A>T

2 papers

NM_002019.4

p.R280Q

c.839G>A

3 papers

NM_002019.4

p.R280*

c.838C>T

1 paper

NM_002019.4

p.V278_R279delFs

c.834_837del4

1 paper

NM_002019.4

p.R279T

c.836G>C

1 paper

NM_002019.4

p.D283V

c.848A>T

1 paper

NM_002019.4

p.R279fs

c.835_836fs

1 paper

NM_002019.4

p.Q284*

c.850C>T

1 paper

NM_002019.4

p.V278V

c.834A>C

1 paper

NM_002019.4

p.S285R

c.855C>G

1 paper

NM_002019.4

p.R275T

c.824G>C