Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002019.4

p.T265T

c.795C>G

Surrounding Variants

1 paper

NM_002019.4

p.T265I

c.794C>T

1 paper

NM_002019.4

p.W266*

c.797G>A

1 paper

NM_002019.4

p.W266*

c.798G>A

1 paper

NM_002019.4

p.Y268H

c.802T>C

4 papers

NM_002019.4

p.V262V

c.786T>C

1 paper

NM_002019.4

p.Y268Y

c.804C>T

1 paper

NM_002019.4

p.P269S

c.805C>T

1 paper

NM_002019.4

p.N259_R261del3

c.775_782del9

1 paper

NM_002019.4

p.D270N

c.808G>A

1 paper

NM_002019.4

p.T260T

c.780G>A

1 paper

NM_002019.4

p.P257L

c.770C>T

1 paper

NM_002019.4

p.T253N

c.758C>A