Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

13 papers

NM_002019.4

p.P237L

c.710C>T

Surrounding Variants

1 paper

NM_002019.4

p.R238C

c.712C>T

1 paper

NM_002019.4

p.R238L

c.713G>T

2 papers

NM_002019.4

p.R238H

c.713G>A

1 paper

NM_002019.4

p.T236A

c.706A>G

1 paper

NM_002019.4

p.V240A

c.719T>C

1 paper

NM_002019.4

p.L242*

c.725T>G

1 paper

NM_002019.4

p.L242*

c.725T>A

1 paper

NM_002019.4

p.L243I

c.727C>A

2 papers

NM_002019.4

p.G245C

c.733G>T

1 paper

NM_002019.4

p.G245S

c.733G>A

1 paper

NM_002019.4

p.T228A

c.682A>G

1 paper

NM_002019.4

p.N227S

c.680A>G